Sublingual Immunotherapy (SLIT) Treatment in London

Needle-free allergy treatment for lasting relief from hay fever and environmental allergies

We provide specialist sublingual immunotherapy treatments in London for hay fever, pollen, dust mite, and animal allergies. Our evidence-based approach offers convenient allergy drops and tablets that you take at home, helping you achieve long-term relief from persistent allergic symptoms.

Proven needle-free allergy treatment for environmental allergies
Convenient home treatment with allergy drops and tablets
Long-term relief reducing need for daily medications
Speak to our Team
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How sublingual immunotherapy works

Sublingual immunotherapy involves placing small tablets or drops containing allergen extracts under your tongue daily to retrain your immune system. Over time, this reduces sensitivity to allergens such as grass pollen, tree pollen, house dust mites, and pet dander, providing lasting relief from allergic symptoms.
The treatment works by:
Delivering controlled allergen doses under the tongue for immune exposure
Gradually building tolerance through consistent daily treatment at home
Retraining your immune system to recognise allergens as harmless
Reducing the severity and frequency of allergic reactions over time

This process creates long-term desensitisation, offering a disease-modifying approach to allergy management rather than just symptom relief. The effects continue for years after completing the treatment course.

Our approach to sublingual immunotherapy

Sublingual immunotherapy involves placing small tablets or drops containing allergen extracts under your tongue daily to retrain your immune system. Over time, this reduces sensitivity to allergens such as grass pollen, tree pollen, house dust mites, and pet dander, providing lasting relief from allergic symptoms.

Your treatment journey

Comprehensive assessment

Conduct thorough allergy testing to confirm specific environmental allergens

Suitability evaluation

Evaluate your suitability for SLIT based on symptom severity and medical history

Personalised protocol

Select the most appropriate SLIT formulation for your specific allergies

Ongoing monitoring

Provide comprehensive guidance for safe home administration and monitoring

The science of sublingual immunotherapy

Sublingual immunotherapy works by delivering tiny, carefully measured doses of an allergen under the tongue, where they are absorbed through specialised immune cells in the oral mucosa. This gentle exposure trains your immune system over time to become less reactive.

At the core of this process is the stimulation of regulatory T-cells, which help suppress the allergic response and promote tolerance. Like oral immunotherapy, SLIT encourages the production of IgG4 blocking antibodies that interfere with the activity of IgE antibodies, the ones responsible for triggering allergic reactions.

By gradually shifting the immune response in a safer, more targeted way, sublingual immunotherapy helps reduce symptoms and build lasting desensitisation.

Types of sublingual immunotherapy

We offer comprehensive SLIT options for various environmental allergies, using licensed treatments and established protocols for optimal safety and effectiveness.
Hay fever
Our hay fever immunotherapy includes licensed SLIT tablets for grass and tree pollen allergies.
Treatments include:
Grazax treatment: Licensed for grass pollen allergic rhinitis and conjunctivitis in adults and children over 5 years
Itulazax treatment: Licensed for birch tree pollen allergic rhinitis in adults, used off-label in children
Grass pollen allergy drops: Comprehensive treatment for summer hay fever symptoms
Dust mite allergy
Our house dust mite immunotherapy provides year-round relief for perennial allergy symptoms affecting sleep and daily activities.
Treatments include:
Acarizax treatment: Licensed for house dust mite-induced allergic rhinitis in adults and adolescents with persistent moderate to severe symptoms.
House dust mite allergy drops: Customised treatment for year-round symptoms including nasal congestion and sleep disruption.
Pet and animal allergy
Our pet allergy immunotherapy offers treatment options for cat and dog dander allergies, helping maintain quality of life around beloved pets.
Treatments include:
Cat dander immunotherapy drops: Treatment for cat allergen sensitivity allowing safer cohabitation with feline companions.
Dog dander allergy treatment: Specialised protocols for dog allergen desensitisation in various breeds and exposure levels.
Mixed pet allergen therapy: Comprehensive treatment for patients with multiple pet sensitivities.

Not sure which treatment is right? We’re here to help.

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Why choose us for sublingual immunotherapy?

Led by Professor Gideon Lack, our allergy specialist London team offers comprehensive expertise in SLIT treatment:
World-leading specialists in allergic conditions and environmental allergies
Access to licensed SLIT formulations and established treatment protocols
Comprehensive safety monitoring with first-dose supervision
Personalised treatment plans tailored to your specific allergic profile
Ongoing support throughout your treatment journey
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Eczema
“As far as our family is concerned, Professor Lack is a miracle worker. We trust his advice implicitly and are very lucky to have him as our daughter’s specialist.”
Eczema
28th Sept 2024
Eczema
verified patient

Pioneering research, personalised care

Our approach combines our team's groundbreaking research into the causes and treatment of allergies with deeply personalised care. As global leaders in allergy prevention and treatment, we're dedicated to transforming lives through early intervention and innovative therapies. From food allergies and asthma to eczema and anaphylaxis, we provide evidence-based treatments tailored to each patient's needs.
More About the LACK Clinic
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Frequently asked questions

Who are candidates for sublingual immunotherapy?
SLIT for hay fever sufferers is most suitable for patients with moderate to severe allergic rhinitis, conjunctivitis, or allergic asthma caused by confirmed environmental allergens. Ideal candidates include those with grass pollen, tree pollen, house dust mite, or pet allergies who experience persistent symptoms despite conventional treatments. Both adults and children over 5 years can benefit from treatment. We conduct comprehensive allergy testing to confirm specific triggers and assess whether sublingual immunotherapy is appropriate for your condition.
How does SLIT vs allergy shots compare?
Sublingual immunotherapy offers several advantages over traditional allergy shots. SLIT is needle-free and can be taken at home daily, eliminating the need for frequent clinic visits. The safety profile is generally more favourable, with most side effects being mild mouth itching that resolves quickly. While allergy shots may work faster for some patients, SLIT provides comparable long-term effectiveness with greater convenience and reduced risk of severe allergic reactions.
What is the SLIT treatment process and timeline?
Starting SLIT for hay fever involves an initial consultation and allergy testing to confirm your triggers. The first dose is taken under medical supervision to ensure proper technique and tolerance. You then continue daily doses at home for three years, with annual reviews to assess progress. Most patients begin noticing reduced symptoms after 6-12 months, with maximum benefit typically achieved during the second year. The effects continue for years after completing treatment.
What are the benefits and side effects of SLIT treatment?
Sublingual immunotherapy safety is well-established, with most side effects being mild and temporary. Common effects include mouth itching, throat irritation, or mild stomach discomfort, particularly during the first week of treatment. These typically resolve within 20 minutes. Benefits include long-term allergy relief, reduced medication dependence, convenience of home treatment, and potential prevention of new allergies or asthma development. Severe reactions are extremely rare with SLIT.
Is sublingual immunotherapy effective for children?
Sublingual immunotherapy for children is highly effective and safe when started at age 5 or older. Children often respond very well to treatment, and early intervention may help prevent the development of additional allergies or asthma. The needle-free format makes it particularly suitable for young patients, and the convenience of home administration helps maintain consistent treatment. Our paediatric specialists provide comprehensive support to families throughout the treatment journey.

Ready to find long-term relief from hay fever and allergies?

Our specialist team can help you determine whether oral immunotherapy is appropriate for your specific food allergies and develop a safe, effective treatment plan for lasting protection. As a private practice, we'll provide clear information about SLIT cost and treatment investment during your consultation.
Speak to Our Team
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